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Although those are the best for muscle growth, you will also see good development of muscles using S4 Andarine and LGD-4033 Ligandrol.”
The authors then go on to highlight two ways that these substances can be used to increase muscle-building, including by creating the appropriate conditions in the body for growth – “a combination effect of both andarine and ligandrol in vivo and anandamide in vitro.”
“The effects that andarine and ligandrol have on muscle growth are not limited to the growth of the fast-twitch muscle fibers. In addition, andarine has been reported to increase the mass of the fast-twitch fiber (type I), an effect believed to be mediated by an increased number of myonuclei and sarcomeres [neurons],” say the authors. “The effects of ligandrol on fast-twitch fibers have not been well studied, but it could have potential muscle-growth effects in humans.”
A study by Wang et al, published in a recent issue of the Asian Journal of Andrology and Sports Medicine, showed that after a period of 2 months of supplementation of LGD-4033 on the thigh muscle of young men, significant increases in type I fibers were observed.
Andarine is a natural substance that is found in a lot of fruit. As such, it can be found in fruits such as apples and strawberries. It occurs naturally in the body because it is found in many fruits and vegetables.
The use of andarine is not restricted to the human body. A study in this research by the University of Texas in Dallas found that andarine can be used to treat inflammatory arthritis and chronic pain in mice.
“We showed that treatment with LGD-4033 produced a significant reduction in the expression of the type I interleukin (IL)-6 and IL-12 proteins in human neutrophils,” said Dr. Richard S. Brown, lead author of that study.
“These effects were demonstrated in the absence of immunosuppressive treatment and also after 5, 10, 15 or 20 days of treatment,” he added.
So, as an example, the use of LGD-4033 on the hip muscles of mice increased the function of specific immune cells called macrophages in the tissue.
“In order to obtain functional human hip joints, LGD-4033 is combined with another agent that activates the transcription factor SERT (serotonin transporter), which is an important regulator of inflammation,” the study said. “This combined treatment of LGD-4033 and SERT increases the production of prostaglandin E
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